Self-reported sleep disturbances linked to higher risk for Alzheimer's disease in men
In a new study, researchers from Uppsala
University demonstrate that elderly men with self-reported sleep
disturbances run a higher risk of developing Alzheimer's disease
than men without self-reported sleep disturbances. The results are
published in the scientific journal Alzheimer's &
The researchers followed more than 1,000 men, who were initially
50 year old, between the years 1970 and 2010. The results of the
study show that self-reported sleep disturbances were linked to an
increased risk for Alzheimer's disease during the 40-year follow-up
period, particularly if they occurred late in life. The data
suggest that a regular good night's sleep could support brain
health in men.
'We demonstrate that men with self-reported sleep disturbances run
a 1.5-fold higher risk to develop Alzheimer's disease than those
without reports of sleep disturbances during a 40-year follow-up
period. The later the self-reported sleep disturbance was found the
higher the risk was for developing Alzheimer's disease. These
findings suggest that strategies aimed at improving sleep quality
in late life may help reduce the risk to develop Alzheimer's
disease', says Christian Benedict, sleep researcher at Uppsala
University, who led the study.
"Importantly, there are several lifestyle factors, such as
exercise, that can influence your brain's health. Thus, it must be
borne in mind that a multifaceted lifestyle approach comprising
good sleep habits is essential for maintaining brain health as you
age," says Christian Benedict.
In an earlier article published in the journal Sleep, Christian
Benedict and colleagues showed that a single night of total sleep
deprivation increased blood concentrations of brain molecules in
young men that typically rise in blood upon acute brain damage.
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